Registration Dossier
Registration Dossier
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EC number: 226-558-7 | CAS number: 5424-01-1
Density
Administrative data
- Endpoint:
- relative density
- Remarks:
- Other density types indicated (migrated information): density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 February 2013 - 28 March 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study has been performed in accordance with the EC A.2 and OECD 103 guidelines and complied with the principles of GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- GLP compliance:
- yes
- Type of method:
- air comparison pycnometer (for solids)
Test material
- Reference substance name:
- 3-aminopyrazine-2-carboxylic acid
- EC Number:
- 226-558-7
- EC Name:
- 3-aminopyrazine-2-carboxylic acid
- Cas Number:
- 5424-01-1
- Molecular formula:
- C5H5N3O2
- IUPAC Name:
- 3-aminopyrazine-2-carboxylic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): Amiloride Compound 5
- Description: Tan powder
- Storage condition of test material: In refrigerator (2-8°C) protected from light, desiccated
- Other: Reactive to light, moisture and oxygen
Constituent 1
Results and discussion
Densityopen allclose all
- Type:
- relative density
- Density:
- 1.62 g/cm³
- Temp.:
- 20 °C
- Type:
- density
- Density:
- 1.62 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: Mean of 1.617 and 1.627 g/cm^3
Any other information on results incl. tables
Mean of 1.617 and 1.627 g/cm^3
Applicant's summary and conclusion
- Conclusions:
- The relative density of Amiloride Compound 5 at 20°C was determined to be 1.62 using a gas comparison pycnometer (GLP-compliant study in accordance with EC A.3, OECD 109 and EPA OPPTS 830.7300).
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