Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 916-329-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Abiotic degradation
Air: No experimental data on the phototransformation of the substance in air are available. Based on estimation with the QSAR model AopWin (v1.92), in air the substance undergoes rapid degradation after reaction with hydroxyl radicals. The DT50 -value after reaction with hydroxyl radicals is ca. 4 hours. This indicates that the substance is not a long-range transported chemical in air according to the UNECE criteria (http://www.unece.org/fileadmin/DAM/env/documents/2000/ece/eb/ece%20eb%20air.60.e.pdf). This half-life will not be used for the CSA because it is a calculated and not an experimental value. No ozone reaction could be calculated.
Water: The substance is not expected to hydrolyse in absence of hydrolysable groups. Based on this the half-life in water is expected to be > 1yr.
Biotic degradation
The ready biodegradability of Floralozone was investigated in a study conducted in accordance with OECD TG 301D (Closed Bottle test). The test substance biodegrades for 2 % during 28 days inoculation and is therefore considered not readily biodegradable.
Bioaccumulation
Aquatic organisms: The bioaccumulation potential of Floralozone in fish was determined in a study according to Japanese national guidelines equivalent to OECD TG 305 and in compliance with GLP criteria. From this study it can be seen that the substance is not bioaccumulating because no substance was found at the start of the depuration phase. The limit of detection was 160 ng/g fish (160 ug/kg). Using this detection limit a worst case BCF of <132 L/kg was determined (normalised to a lipid content of 5%).
Terrestrial organisms: The BCF for terrestrial organisms (earthworm) was calculated using the QSAR of Jager (1998), which is incorporated in the EUSES model, and yielded a value of 152 L/kg ww.
Transport and distribution
Adsorption/Desorption: The adsorption coefficient of Floralozone was tested in an HPLC screening method OECDTG 121. The substance showed two peaks one peak of 860 (log Koc 2.94) and another one 1200 (logKoc 3.08). It is not clear which peak belongs to which constituent, therefore an average is of the two values will be used for the risk characterisation: Log Koc is 3.01.
Henry coefficient: To assess the volatilisation potential of the substance a Henry’s law constant was calculated which showed a value of 1.03 Pa·m3/mol (at 12 °C). Based on this value partitioning from water to air may be expected to be low.
Distribution:
Based on Level III environmental distribution modelling using EPISUITE (assuming equal and continuous releases to air, water and soil) using the CAS number 67634-15-5 (the main constituent), it is estimated that the majority of the substance released to the environment will partition mainly into soil (79.8%) and water (19.7%) with minor amounts to air (0.22%) and sediment (0.3%).
The SimpleTreat model, which is incorporated in EUSES, simulates the distribution of the substance in a Sewage Treatment Plant. Model calculations show that 0% of the substance will be degraded and the distribution to water, sludge and air is 87.1, 11.3 and 1.66%.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
