sulfuric acids, C9-11-iso-C10 rich, alkyl esters, sodium salt

Acute Toxicity: oral

Administrative data

Endpoint:

acute toxicity: oral

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Similar to Guideline study with acceptable restrictions.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1978

Report date:

1978

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 401 (Acute Oral Toxicity)

Deviations:

yes

Remarks:

e.g. limited data on test substance

GLP compliance:

no

Remarks:

Study was conducted prior to implementation of GLP.

Test type:

standard acute method

Limit test:

no

Test material

Test material information

Constituent 1

Reference substance name:

Sodium etasulfate

EC Number:

204-812-8

EC Name:

Sodium etasulfate

Cas Number:

126-92-1

Molecular formula:

C8H18O4S.Na

IUPAC Name:

sodium 2-ethylhexyl sulfate

Test animals

Species:

rat

Strain:

other: Tif RAI f

Sex:

male/female

Administration / exposure

Route of administration:

oral: gavage

Vehicle:

CMC (carboxymethyl cellulose)

Doses:

100, 1000, 3000, 6000, 7000, 8000, 10000, 12000 and 15000 mg/kg bw

No. of animals per sex per dose:

10

Control animals:

no

Results and discussion

Effect levels

Effect levels 1

Sex:

male/female

Dose descriptor:

LD50

Effect level:

7 570 mg/kg bw

Based on:

test mat.

Effect levels 2

Sex:

male/female

Dose descriptor:

LD50

Effect level:

2 840 mg/kg bw

Based on:

act. ingr.

Applicant's summary and conclusion

Interpretation of results:

other: CLP/EU GHS criteria not met, no classification required according to Regulation (EC) No. 1272/2008.