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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 947-369-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Principles of method if other than guideline:
- Information on method and guideline not stated
- GLP compliance:
- not specified
- Water solubility:
- 34 vol%
- Temp.:
- 25 °C
- pH:
- 6 - 8
- Remarks on result:
- other: This value is the weight by weight percent as sold on the market.
- Key result
- Water solubility:
- >= 430 g/L
- Temp.:
- 25 °C
- pH:
- ca. 6 - ca. 8
- Remarks on result:
- other: The source reports the substance as "soluble in water" This value has been derived by the reviewer and is equivalent to the above value in g/l. The temperature is not stated in the source but this has been assumed as ambient temperature.
- Conclusions:
- HMDTMP-xNa was reported as soluble in water at pH 6-8 (430 g/L). Full details are not available and the reliability is unassignable.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Principles of method if other than guideline:
- Information on method and guideline not stated
- GLP compliance:
- no
- Type of method:
- other: Not reported
- Key result
- Water solubility:
- 15 000 mg/L
- Remarks on result:
- other: No information on pH and temperature stated
- Conclusions:
- HMDTMP-H was reported as very soluble in water in a secondary literature. The original reference was not available for review and no further information is available. The reliability of this result is not assignable.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Principles of method if other than guideline:
- Information on method and guideline not stated
- GLP compliance:
- not specified
- Water solubility:
- 30 - 40 vol%
- Temp.:
- 25 °C
- pH:
- ca. 7
- Remarks on result:
- other: This value is the weight by weight percent as sold on the market. An average value of 35% was used by the reviewer.
- Key result
- Water solubility:
- >= 440 g/L
- Temp.:
- 25 °C
- pH:
- ca. 7
- Remarks on result:
- other: The source reported the solubility of the substance as "miscible in all proportions". This value has been derived by the reviewer and is equivalent to the above value in g/l. The temperature is not stated in the source but this has been assumed
- Conclusions:
- HMDTMP-xNa was reported as miscible in all proportions with water an pH ~7 (440 g/L). Full details are not available and the reliability is unassignable.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Principles of method if other than guideline:
- Information on method and guideline not stated
- Water solubility:
- 30 vol%
- Temp.:
- 20 °C
- pH:
- ca. 5.8 - ca. 6.3
- Remarks on result:
- other: This value is the weight by weight percent as sold on the market.
- Key result
- Water solubility:
- >= 380 g/L
- Temp.:
- 20 °C
- pH:
- ca. 5.8 - ca. 6.3
- Remarks on result:
- other: The source reported the solubility of the substance as "fully miscible with water". This value has been derived by the reviewer and is equivalent to the above value in g/l.
- Conclusions:
- HMDTMP-H was reported as fully miscible with water at a temperature of 20°C and pH of 5.8 - 6.3 (380 g/L). Full details are not available and the reliability is unassignable.
Referenceopen allclose all
Description of key information
Water solubility [HMDTMP (4-7Na)]: The substance is very soluble in water and has an average water solubility value of 410 g/L at ambient conditions as described in a secondary sources.
Key value for chemical safety assessment
- Water solubility:
- 410 g/L
- at the temperature of:
- 25 °C
Additional information
The substance HMDTMP (4-7Na) (and its analogues) are known to be highly hydrophilic and extremely water-soluble. Although supplier's literature is much less detailed than laboratory study reports, given the range of values expected for these types of substance, the uncetainty is not significant in respect of environmental exposure or human health exposure modelling. Typical concentrations of aqueous solutions in commercial supply provides weight of evidence of high loadings. Water solubility in the range 380 - 440 g/L were reported for the sodium salt of HMDTMP. Therefore, a typical value of 410 g/L was determined for many commercial solutions.
Phosphonate salts are highly water soluble and are supplied as aqueous solutions. Free acids are less soluble than the salts; however, aqueous solutions in excess of l % active material can be prepared. The aqueous solution of sodium and potassium salts are miscible in water. A water solubility value of 15000 mg/L was reported for the parent acid in a secondary source to which no reliability could be assigned.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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