Registration Dossier
Registration Dossier
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EC number: 231-912-9 | CAS number: 7778-74-7
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption, other
- Remarks:
- general evaluations of perchlorate salts
- Type of information:
- other: general evaluations of perchlorate salts
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Reviews and evaluations from accepted governmental offices are used for the eevaluation of the dermal absorption.
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization
- Author:
- United States Environmental Protection Agency
- Year:
- 2 002
- Reference Type:
- review article or handbook
- Title:
- Toxicological Profile for Perchlorates
- Author:
- Agency for Toxic Substances & Disease Registry
- Year:
- 2 008
- Reference Type:
- review article or handbook
- Title:
- Perchlorate Toxicity and Risk Assessment
- Author:
- David R. Mattie, Joan Strawson, Jay Zhao
- Year:
- 2 006
- Bibliographic source:
- U.S. Air Force Research; US Department of Defense
- Reference Type:
- review article or handbook
- Title:
- SUBSTANCE EVALUATION CONCLUSION as required by REACH Article 48 and EVALUATION REPORT for sodium perchlorate EC No 231-511-9 CAS No 7601-89-0
- Author:
- BAuA Federal Institute for Occupational Safety and Health Germany
- Year:
- 2 016
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Reviews and evaluations on soluble perchlorate salts, including potassium perchlorate, are available from US and European offices. They all conclude that dermal uptake is unlikely because perchlorate ions are rarely absorbed through skin. Based on all widely accepted evaluations an absorption facor of 2% can be assumed for potassium perchlorate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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