Registration Dossier

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
The 4th of Decemebr, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
no guideline available
GLP compliance:
no
Specific details on test material used for the study:
To check this parameter the sample was pulverized.
Key result
Medium:
n-octanol
Solubility:
> 39.7 - < 43 g/L
Temp.:
20 °C
Test substance stable:
yes
Conclusions:
Preliminary test: Ester B solubility in Octanol > 33,3 g/L but < 50 g/L
Final test: Ester B solubility in Octanol > 39,7 g/L but < 43 g/L
Executive summary:

Octanol solubility with the Flask Method was performed on Ester B, with a preliminary study and a final study.

The results, based on the visual check are here reported:

Preliminary test: Ester B solubility in Octanol  > 33,3 g/L, < 50 g/L

Final test: Ester B solubility in Octanol  > 39,7 g/L, < 43 g/L

Description of key information

Key value for chemical safety assessment

At the temperature of:
20 °C
Solubility in organic solvents at 20°C:
43 g/L

Additional information

The solubility of Ester B in octanol was evaluated using the Flask Method, with a preliminary study and a final study.

The results, based on the visual check, were found to be:

Final test: Ester B solubility in Octanol between 39.7 and 43.0 g/L

For the purpose of the CSA, a worst-case scenario is used and the maximal value is accepted: solubility in octanol = 43.0 g/L.

Categories Display