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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental start date 18 January 2017 Experimental completion date 15 February 2017
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
according to guideline
EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
GLP compliance:
yes (incl. QA statement)
Oxygen conditions:
Inoculum or test system:
activated sludge, domestic, non-adapted
Details on inoculum:
A mixed population of sewage treatment micro-organisms was obtained on 16 January 2017 from the final effluent stage of the Severn Trent Water Plc sewage treatment plant at Loughborough, Leicestershire, UK, which treats predominantly domestic sewage.
Duration of test (contact time):
ca. 28 d
Key result
% degradation (O2 consumption)
ca. 0
Sampling time:
28 d
Validity criteria fulfilled:
Interpretation of results:
not readily biodegradable
The test item attained 0% biodegradation after 28 days and therefore cannot be considered as readily biodegradable under the strict terms and conditions of OECD Guideline No. 301F.
Executive summary:


This study was performed to assess the ready biodegradability of the test substance in an aerobic aqueous medium. The method was designed to be compatible with the following guideline: OECD Guidelines for Testing of Chemicals (1993) No. 301F, 'Ready Biodegradability; Manometric respirometry. Adopted 17th July 1992'

Results & Conclusions

The test substance attained 0% degradation after 28 days and therefore cannot be considered to be readily biodegradable.

Description of key information

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information