Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Environmental fate

Degradation

Readily biodegradable: 74.6% after 28 d (OECD 301 F)

Bioaccumulation

log Kow < - 1.7 (pH 7, 23 °C , OECD 107)

 

Aquatic acute toxicity

Fish

LC50 (96 h) > 100 mg/L (nominal, OECD 203, D. rerio)

Aquatic invertebrates

EC50 (48 h) > 100 mg/L (nominal, OECD 202, D. magna)

Aquatic algae

ErC50 (72 h) > 100 mg/L (nominal, OECD 201, P. subcapitata)

 

Aquatic chronic toxicity

Aquatic algae

ErC10 (72 h) > 100 mg/L  (nominal, OECD 201, P. subcapitata)

 

Classification according to CLP

According to the available data for the aquatic hazard of N-Acetyl-DL-tryptophan (CAS 87-32-1) compiled above, no short-term toxicity to aquatic organisms of all three trophic levels (fish, aquatic invertebrates and algae) was recorded and the respective acute effect concentrations are all clearly above 1 mg/L. Furthermore, the substance is readily biodegradable and has a low potential for bioaccumulation. Data for long-term toxicity is available only for algae and no chronic effects were recorded (ErC10 > 100 mg/L). Therefore, the substance is not classified and labelled for environmental hazards, according to the consolidated version of Regulation (EC) No 1272/2008 (dated: 01.01.2017) and further amendments (ATPs).