Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Environmental fate

Degradation

Readily biodegradable: 74.6% after 28 d (OECD 301 F)

Bioaccumulation

log Kow < - 1.7 (pH 7, 23 °C , OECD 107)

 

Aquatic acute toxicity

Fish

LC50 (96 h) > 100 mg/L (nominal, OECD 203, D. rerio)

Aquatic invertebrates

EC50 (48 h) > 100 mg/L (nominal, OECD 202, D. magna)

Aquatic algae

ErC50 (72 h) > 100 mg/L (nominal, OECD 201, P. subcapitata)

 

Aquatic chronic toxicity

Aquatic algae

ErC10 (72 h) > 100 mg/L  (nominal, OECD 201, P. subcapitata)

 

Classification according to CLP

According to the available data for the aquatic hazard of N-Acetyl-DL-tryptophan (CAS 87-32-1) compiled above, no short-term toxicity to aquatic organisms of all three trophic levels (fish, aquatic invertebrates and algae) was recorded and the respective acute effect concentrations are all clearly above 1 mg/L. Furthermore, the substance is readily biodegradable and has a low potential for bioaccumulation. Data for long-term toxicity is available only for algae and no chronic effects were recorded (ErC10 > 100 mg/L). Therefore, the substance is not classified and labelled for environmental hazards, according to the consolidated version of Regulation (EC) No 1272/2008 (dated: 01.01.2017) and further amendments (ATPs).

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