Registration Dossier
Registration Dossier
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EC number: 254-159-8 | CAS number: 38861-78-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-[4-(2-methylpropyl)phenyl]ethan-1-one
- EC Number:
- 254-159-8
- EC Name:
- 1-[4-(2-methylpropyl)phenyl]ethan-1-one
- Cas Number:
- 38861-78-8
- Molecular formula:
- C12H16O
- IUPAC Name:
- 1-[4-(2-methylpropyl)phenyl]ethan-1-one
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum: Activated sludge from a municipal sewage plant
Origin: Municipal waste water treatment plant Mannheim, Germany - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 20 mg/L
- Based on:
- TOC
- Initial conc.:
- ca. 24 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD 301B
- Additional substrate: no
- Solubilising agent (type and concentration if used): no
- Test temperature: 22 +/- 2 °C
- pH: 7.1 - 7.4
- pH adjusted: yes, to pH 7.4
- Aeration of dilution water: yes
- Continuous darkness: yes/no
TEST SYSTEM
- Culturing apparatus: brown glass bottles
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: aeration with CO2 free air
- Test performed in closed vessels due to significant volatility of test substance: no
- Test performed in open system: yes
- Details of trap for CO2 and volatile organics if used: KOH
SAMPLING
- Sampling frequency: variable
- Sterility check if applicable: no
- Sample storage before analysis: no
CONTROL AND BLANK SYSTEM
- Inoculum blank: 1
- Toxicity control: 1
STATISTICAL METHODS: not applicable
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0 - 10
- Sampling time:
- 12 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 10 - 20
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 40 - 50
- Sampling time:
- 24 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 50 - 60
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- day 2: 0 - 10 %
day 5: 30 - 40 %
day 8: 60 - 70 %
day 14: 80 - 90 %
day 28: 90 - 100 %
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
