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EC number: 254-159-8 | CAS number: 38861-78-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-[4-(2-methylpropyl)phenyl]ethan-1-one
- EC Number:
- 254-159-8
- EC Name:
- 1-[4-(2-methylpropyl)phenyl]ethan-1-one
- Cas Number:
- 38861-78-8
- Molecular formula:
- C12H16O
- IUPAC Name:
- 1-[4-(2-methylpropyl)phenyl]ethan-1-one
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum: Activated sludge from a municipal sewage plant
Origin: Municipal waste water treatment plant Mannheim, Germany - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 20 mg/L
- Based on:
- TOC
- Initial conc.:
- ca. 24 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD 301B
- Additional substrate: no
- Solubilising agent (type and concentration if used): no
- Test temperature: 22 +/- 2 °C
- pH: 7.1 - 7.4
- pH adjusted: yes, to pH 7.4
- Aeration of dilution water: yes
- Continuous darkness: yes/no
TEST SYSTEM
- Culturing apparatus: brown glass bottles
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: aeration with CO2 free air
- Test performed in closed vessels due to significant volatility of test substance: no
- Test performed in open system: yes
- Details of trap for CO2 and volatile organics if used: KOH
SAMPLING
- Sampling frequency: variable
- Sterility check if applicable: no
- Sample storage before analysis: no
CONTROL AND BLANK SYSTEM
- Inoculum blank: 1
- Toxicity control: 1
STATISTICAL METHODS: not applicable
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0 - 10
- Sampling time:
- 12 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 10 - 20
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 40 - 50
- Sampling time:
- 24 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 50 - 60
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- day 2: 0 - 10 %
day 5: 30 - 40 %
day 8: 60 - 70 %
day 14: 80 - 90 %
day 28: 90 - 100 %
Applicant's summary and conclusion
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