Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

First-aid measures

Description of first aid measures

· After inhalation:

Remove the victim to fresh air, give artificial respiration or oxygen if required. Get medical attention

immediately if breathing difficult is continued.

· After skin contact:

Wash with soap & water, discard contaminated clothing & shoes. Get medical attention immediately.

· After eye contact: Flush with water atleast for 15 minutes, get medical attention if irritation persists.

· After swallowing: Do not induce vomitting. Give milk & water, obtain medical attention immediately.

· Most important symptoms and effects, both acute and delayed No further relevant information available.

· Information for doctor: Provide symptomatic treatment.

· Indication of any immediate medical attention and special treatment needed

No further relevant information available.


Fire-fighting measures

Extinguishing media

· Suitable extinguishing agents:

Use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray, dry chemical, carbon

dioxide, or chemical foam.

· Special hazards arising from the substance or mixture

In combustion emits toxic fumes. Forms explosive air-vapour mixture.Carbon oxides.

· Advice for firefighters

For fires involving this material, do not enter any enclosed or confined fire space without proper protective

equipments including self contained breathing apparatus.

· Protective equipment:

Use PVC or rubber gloves, aprons, gumboots, goggles, face shield, overall breathing apparatus if required.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid direct contact with the substance. Ensure there is sufficient ventilation of the area.

Do not handle in a confined space. Avoid the formation or spread of mists in the air.

· Environmental precautions: Do not discharge into drains or rivers. Contain the spillage using bunding.

· Methods and material for containment and cleaning up:

Eliminate potential source of ignition, stop leak if possible. Absorb the spill content in clay, sand, earth. Water

disposal method. Let the spillage go to the chemical sewer. Flush small spillages with plenty of water. Dispose the residue and flush properly.

· Reference to other sections

See Section 7 for information on safe handling.

See Section 8 for information on personal protection equipment. See Section 13 for disposal information.

Handling and storage

Precautions for safe handling

Avoid direct contact with the substance. Ensure there is sufficient ventilation of the area.

Do not handle in a confined space. Avoid the formation or spread of mists in the air. Smoking is forbidden. Use non-sparking tools. Only use in fume hood.

· Information about protection against explosions and fires:

Keep ignition sources away - Do not smoke.

Protect against electrostatic charges.

· Conditions for safe storage, including any incompatibilities

Store the material in cool, clean, well ventillated fireproof storage areas.

· Storage:

· Requirements to be met by storerooms and receptacles:

Keep away from open flames, hot surfaces and sources of ignition.

Store in a tightly closed container.

· Information about storage in one common storage facility: Store away from incompatible materials.

· Further information about storage conditions: Do not pressurise the containers. Use leakproof containers.

· Specific end use(s) It is used for the manufacturing Ibuprofen, an anti-inflammatory, analgesic bulk drug.

Transport information

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

Additional information about design of technical systems: No further data; see item 7.

· Control parameters

If the engineering controls or work practices are not adequate to prevent the exposure to harmful level, the use

of recommended protective equipments are advised to prevent the exposures. Use in well ventilated area.

· Components with limit values that require monitoring at the workplace: Not required.

· Additional information: The lists that were valid during the creation were used as basis.

· Exposure controls

· Personal protective equipment:

· General protective and hygienic measures:

Keep away from foodstuffs, beverages and feed.

Immediately remove all soiled and contaminated clothing. Wash hands before breaks and at the end of work.

Avoid contact with the skin.

Avoid contact with the eyes and skin.

· Breathing equipment:

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure

use respiratory protective device that is independent of circulating air.

· Protection of hands:

Protective gloves

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.

Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.

Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

· Material of gloves

The selection of the suitable gloves does not only depend on the material, but also on further marks of quality

and varies from manufacturer to manufacturer.

· Penetration time of glove material

The exact break through time has to be found out by the manufacturer of the protective gloves and has to be


· Eye protection:

Tightly sealed goggles

· Body protection: Wear appropriate protective clothing to prevent skin exposure.

Stability and reactivity


· Chemical stability Stable under normal temperatures and pressures.

· Thermal decomposition / conditions to be avoided: Ignition sources, excess heat.

· Possibility of hazardous reactions Voilent reactions possible with strong oxidizing agent.

· Conditions to avoid Ignition sources, excess heat.

· Incompatible materials: Oxygen & strong oxidising agents.

· Hazardous decomposition products: No decomposition products was found.

Disposal considerations

Waste treatment methods

· Recommendation:

Use material for its intended purpose or recycle if possible. Material if it must be discarded, may meet the

requirement of hazardous waste as defined by local regulatory authorities. If this material is classified as hazardous waste, federal laws require disposal at the licensed hazardous waste disposal facility.