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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
November 2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Estimtion method (EPI Suite) recommended by IUCLID Guidance Documents.

Data source

Reference
Reference Type:
other: software program
Title:
Estimation Programs Interface (EPI) Suite™ v3.20 for Microsoft® Windows,
Author:
Anonymous
Year:
2009
Bibliographic source:
U.S. Environmental Protection Agency, Washington, DC, U.S.A.

Materials and methods

Principles of method if other than guideline:
Properties of the Reference Substance were modeled using EPI Suite v3.20.

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate
EC Number:
243-885-0
EC Name:
2-(2-hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate
Cas Number:
20566-35-2
Molecular formula:
C15H15Br4O7 (one ring component) C8 H2 Br4 O4 . C4 H10 O3 . C3 H8 O2 Unspecified reaction product of the three components
IUPAC Name:
2-(2-hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate
Details on test material:
Modeling was based on Reference Substance.

Radiolabelling:
no

Test conditions

Details on estimation of bioconcentration:
Estimated BCF=39.42 (BCF v2.17).

Results and discussion

Bioaccumulation factor
Remarks on result:
other: BCF was estimated to be 39.

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
Not expected to bioconcentrate/bioaccumulate
Executive summary:

The estimated BCF indicates a lack of bioconcentration potential as does the estimated Log Kow and the potential for hydrolysis.