Registration Dossier
Registration Dossier
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EC number: 813-358-5 | CAS number: 4886-26-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- Regulation (EC) No 440/2008 of 30 May 2008
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.666
- Temp.:
- 25 °C
- pH:
- 2
- Details on results:
- The chromatogram of the test item gave two peaks. With the calibration function log k versus log POW, the corresponding log Pow-values of the major peaks were determined with:
logPow (peak 1) 0.425 +/- 0.001 and
logPow (peak 2) 1.666 +/- 0.000
It is assumed that peak 1 is due to a product of hydrolysi reaction.
Reference
Description of key information
Determination of the log Pow of N-Phenyl-N'-[(phenylamino)sulfonyl]urea using the HPLC method according to OECD 117 resp. EU A.8
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.666
- at the temperature of:
- 25 °C
Additional information
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