Registration Dossier
Registration Dossier
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EC number: 201-132-3 | CAS number: 78-67-1
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1996
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- secondary source
- Title:
- no data
- Author:
- Elf Atochem
- Year:
- 1 996
- Bibliographic source:
- cited in OECD SIDS Final 08/02
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Reference substance 001
- Details on test material:
- - purity: 99.2 %
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- yes, concurrent no treatment
- Amount / concentration applied:
- 100 mg
- Observation period (in vivo):
- approximately one hour, 24, 48 and 72 hours after administration
- Details on study design:
- eyes were not rinsed
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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