Registration Dossier
Registration Dossier
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EC number: 211-402-2 | CAS number: 643-79-8
Endpoint summary
Administrative data
Description of key information
A reliable toxicity study in invertebrates has been conducted for ortho-phthalaldehyde and ais included in the dossier. Further information on algae and fish is available.
Daphnia magna was observed to be the most sensitive species. The related 48-h EC50 determined according to EU method C.2 (acute toxicity for Daphnia magna) was 0.11 mg/L.
Additional information
Data on the freshwater algae Pseudokirchneriella subcapitata as presented on the EPA database (ECOTOX knowlegdebase) is added to the dossier as supplementary information. The reported 96-h EC50 is 184 µg/L, indicating that D. magna is slightly more sensitive than algae.
Regarding toxicity towards microorganisms the following effect concentrations were determined within a test conducted according to the OECD guideline 209:
Total respiration
NOEC = 9.8 mg/L
EC50 = 76.6 mg/L (95 % CI: 48.9 - 143.2 mg/L)
Heterotrophic respiration
NOEC = 3.1 mg/L
EC50 = 33.0 mg/L (95 CI: 24.2 - 48.2 mg/L)
Nitrification
NOEC = 31.3 mg/L
EC50 > 100 mg/L
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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