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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 2009-06-30 to 2009-07-01
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
no guideline followed
Principles of method if other than guideline:
An in-house Dynamic Light Scattering (DLS) based methodology highly adapted to the registered substance was applied.
GLP compliance:
no
Type of method:
other: Dynamic light scattering
No.:
#1
Size:
12.2 nm
Remarks on result:
other: Hydrodynamic diameter
No.:
#2
Size:
11.5 nm
Remarks on result:
other: Hydrodynamic diameter
No.:
#3
Size:
12.6 nm
Remarks on result:
other: Hydrodynamic diameter

First analysis:

Hydrodynamic diameter: 12.2 nm

Standard deviation: 8.4 nm

Second analysis:

Hydrodynamic diameter: 11.5 nm

Standard deviation: 8.4 nm

Third analysis:

Hydrodynamic diameter: 12.6 nm

Standard deviation: 7.6 nm

Mean:

Hydrodynamic diameter: 12.1 nm

Standard deviation: 8.1 nm

The acquisitions were made under very correct conditions, the scattered intensity was at least of the order of 200 to 500 kHz compared to 23 kHz on the solvent.

The sample has an average hydrodynamic diameter of 12.1 nm with a standard deviation of 8.1 nm.

The estimated uncertainties on these values are +/- 20%.

Conclusions:
The sample has an average hydrodynamic diameter of 12.1 nm with a standard deviation of 8.1 nm.
Executive summary:

The substance was tested using an in-house procedure (Dynamic Light Scattering based methodology) in accordance with generally accepted scientific standards and described in sufficient details. The sample has an average hydrodynamic diameter of 12.1 nm, with a standard deviation of the distribution of 8.1 nm.

Description of key information

The sample has an average hydrodynamic diameter of 12.1 nm with a standard deviation of 8.1 nm.

Additional information

An in-house study, performed according to a methodology highly adapted to the registered substance and scored as Klimisch 1, is selected as a key study, giving an average hydrodynamic diameter of 12.1 nm with a standard deviation of 8.1 nm.