Registration Dossier
Registration Dossier
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EC number: 476-890-3 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 9 June 2005 to 13 September 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- 0.13 mg/L
- Temp.:
- 21 °C
- pH:
- 5.75 - 6.68
- Conclusions:
- The water solubility of iron oxide isostearate is 0.13 mg/L at 21°C.
- Executive summary:
The determination of the water solubility of iron oxide isostearate was performed according to OECD guideline No. 105 under GLP-compliance using the column elution method.
The water solubility of the test item is 0.13 mg/L at 21°C.
Reference
Experiment No. |
Flow rate [mL/h] |
Sample No. |
Concentration analysed [µg Fe/mL] |
Concentration calculated [µg Test item/mL] |
Water solubility [µg Test item/mL] |
pH |
1 |
31 |
1 2 3 4 5 6 |
0.019 * 0.019 * 0.040 0.040 0.040 0.040 |
0.064 0.064 0.132 0.132 0.132 0.132 |
0.13 SD =±0.00 |
5.75 5.98 6.27 6.59 6.68 6.66 |
2 |
16 |
7 8 9 10 11 12 |
0.040 0.040 0.040 0.040 0.040 0.040 |
0.132 0.132 0.132 0.132 0.132 0.132 |
0.13 SD =±0.00 |
6.53 6.26 5.94 6.06 6.14 6.18 |
*: outlier = not used for the determination of the mean value
The measured results differ by more than 30%, thus, two results were discarded as outlier. The remaining four results of the 1strun fit very well together with the results of the second run.
Description of key information
The water solubility of the test item is 0.13 mg/L at 21°C.
Key value for chemical safety assessment
- Water solubility:
- 0.13 mg/L
- at the temperature of:
- 21 °C
Additional information
A GLP experimental study, according to OECD guideline 105 and scored as Klimisch 1, is selected as a key study, giving a water solubility of 0.13 mg/L.
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