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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 9 June 2005 to 13 September 2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
data waiving: supporting information
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method
Key result
Water solubility:
0.13 mg/L
Temp.:
21 °C
pH:
5.75 - 6.68

Experiment No.

Flow rate [mL/h]

Sample No.

Concentration analysed [µg Fe/mL]

Concentration calculated [µg Test item/mL]

Water solubility [µg Test item/mL]

pH

 

 

1

 

 

31

1

2

3

4

5

6

0.019 *

0.019 *

0.040

0.040

0.040

0.040

0.064

0.064

0.132

0.132

0.132

0.132

 

0.13

SD =±0.00

5.75

5.98

6.27

6.59

6.68

6.66

 

 

2

 

 

16

7

8

9

10

11

12

0.040

0.040

0.040

0.040

0.040

0.040

0.132

0.132

0.132

0.132

0.132

0.132

 

0.13

SD =±0.00

6.53

6.26

5.94

6.06

6.14

6.18

*: outlier = not used for the determination of the mean value

The measured results differ by more than 30%, thus, two results were discarded as outlier. The remaining four results of the 1strun fit very well together with the results of the second run.

Conclusions:
The water solubility of iron oxide isostearate is 0.13 mg/L at 21°C.
Executive summary:

The determination of the water solubility of iron oxide isostearate was performed according to OECD guideline No. 105 under GLP-compliance using the column elution method.

The water solubility of the test item is 0.13 mg/L at 21°C.

Description of key information

The water solubility of the test item is 0.13 mg/L at 21°C.

Key value for chemical safety assessment

Water solubility:
0.13 mg/L
at the temperature of:
21 °C

Additional information

A GLP experimental study, according to OECD guideline 105 and scored as Klimisch 1, is selected as a key study, giving a water solubility of 0.13 mg/L.