Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data waiving: Data from handbook or collection of data

Data source

Reference
Title:
SIAM 29, 20-22 October 2009, SIDS INITIAL ASSESSMENT PROFILE

Materials and methods

Results and discussion

Applicant's summary and conclusion

Conclusions:
HMDZ undergoes rapid hydrolysis in the presence of water; the half life at pH 7 and 1.5°C is <0.5 minutes. Based on the chemical structure of HMDZ, this hydrolysis is expected to produce ammonia (CAS No. 7664-41-7) and trimethylsilanol (CAS No. 1066-40-6).