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Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vitro / ex vivo
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is classified as skin corrosion, leading to classification as serious eye damage (Category 1)
the study does not need to be conducted because the substance is a strong acid (pH <= 2.0) or base (pH => 11.5) and the available information indicates that it should be classified as serious eye damage (Category 1)
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
Internal company data provided a pH value measured using a standard pH meter.
GLP compliance:
no
pH value:
1
Temp.:
20 °C
Remarks on result:
other: Temperature assumed. Concentration unknown.
Conclusions:
The pH of the test substance was determined to be 1 using a standard pH meter.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion

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