Reaction mass of: N,N'-[1,3-Phenylenebis(methylene)bis[12-hydroxyoctadecanamide], N,N'-hexane-1,6-diylbis(12-hydroxyoctadecanamide) and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide)

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12. Feb. 2019 - 16. May 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Decomposition:

yes

Decomp. temp.:

ca. 310 °C

Remarks on result:

not determinable

Remarks:

The substance decomposes at 138°C.

Conclusions:

As the test item showed signs of decomposition before boiling stage no validity criteria need to be considered. The substance decomposes. A boiling point could not be determined.

Executive summary:

The substance decomposes at 138 °C. A boiling point could not be determined. The boiling point of the decomposition product referring to the pre-test was determined under these circumstances as the second endothermic event. The event could not be completely detected because of the measuring limit of the instrument (445 °C). Beginning of boiling was detected at 347.06 °C (620.21 K) (lowest value) with a peak maximum at 402.82 °C (665.60 K) (highest value). A baseline level underrun was visible in all three determinations.

Reference 2

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

other: see remarks

Version / remarks:

The boiling point was assessed in a preliminary test at the determination of the melting point according to Annex V, EU Method A.1 (Differential Scanning Calorimeter).

Principles of method if other than guideline:

Preliminary test at the determination of the melting point according to Annex V, EU Method A.1 (Differential Scanning Calorimeter). Details of the experimental procedure are not specified.

GLP compliance:

not specified

Type of method:

other: Preliminary test at the determination of the melting point. Details not specified.

Remarks on result:

not determinable

Remarks:

The boiling point has not been determined. In a preliminary test at the determination of the melting point, it was found that at temperatures above 175 °C an exothermic reaction was observed, probably caused by reaction or decomposition of the test substance. After the test the sample appeared to have been molten and had a brown colour.

Conclusions:

The boiling point has not been determined. An exothermic reaction was observed above 175 °C, probably caused by reaction or decomposition of the test substance. After the test the sample appeared to have been molten and had a brown colour.

Executive summary:

The boiling point of 1,3-bis[12-hydroxy-octadecamide-N-methylene]-benzene has not been determined. At the determination of the melting point according to Annex V, EU Method A.1 (Differential Scanning Calorimeter), a preliminary test was carried out (details of the experimental procedure are not specified). Therein, an exothermic reaction was observed above 175 °C, probably caused by reaction or decomposition of the test substance. After the test the sample appeared to have been molten and had a brown colour.

Reference 3

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

92/69/EEC, A2 (Differential scanning calorimetery, ASTM E 537-76 OECD Guideline No. 103)

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Atm. press.:

ca. 101.3 kPa

Decomposition:

yes

Decomp. temp.:

>= 144 °C

Remarks on result:

not determinable

The test substance melted from 115 to 124 °C followed by decomposition from 144 °C. A chemical change was observed between 125 and 140 °C. After the test, sample remains were black and crispy.

Conclusions:

No boiling point was observed for the test substance 12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine. The test substance melted from 115 to 124 °C followed by decomposition from 144 °C. A chemical change was observed between 125 and 140 °C. After the test, sample remains were black and crispy.

Executive summary:

The boiling point of the test substance 12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine was assessed in a guideline study according to EU Method A.2 (Differential scanning calorimetery). No boiling point was observed. The test substance melted from 115 to 124 °C followed by decomposition from 144 °C. A chemical change was observed between 125 and 140 °C. After the test, sample remains were black and crispy.

Description of key information

The substance consists of multiple different constituents with similar chemical structure: N,N'-ethane-1,2-diylbis(12-hydroxyoctadecanamide), N,N'-hexane-1,6-diylbis(12-hydroxyoctadecanamide) and N,N'-[1,3-phenylenebis(methylene)]bis(12-hydroxyoctadecanamide).There are no experimental data on the multi-constituent substance available. The individual constituents and mixtures of structurally similar bisamides are considered suitable read-across substances. In experimental studies on the read-across substances 1,3-bis[12-hydroxy-octadecamide-N-methylene]-benzene, 12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecanamide) decomposition of the test material was observed before the onset of boiling (decomposition temperature: 138 – 175 °C). Since all constituents are structurally similar to each other, the boiling behaviour of the multi-constituent substance is expected to be comparable to the properties of the read-across substances. Therefore, decomposition of the substance at elevated temperatures (> ca. 140 °C) before onset of boiling is expected. Further testing is not considered necessary.