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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 27, 2015 to June 09, 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Specific details on test material used for the study:
Name (as stated in the report): GR-88-0778
Lot No: Batch 6
Aspect: Colourless liquid
Expiration date: March 29, 2017
Key result
Water solubility:
24.5 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
7
Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)The results in Table 1 and curves in Appendix 1 show that there is no significant change of the measured concentrations after 72 h and 96 h. Thus it can be concluded that equilibrium is reached. Thus the results obtained after 72 h and 96 h were averaged, to give the water solubility of GR-88-0778. After rounding off:Solubility of GR-88-0778 in water at 20°C: 24.5 mg/l
Executive summary:

The solubility of GR-88-0778 in ultrapure water was determined according to the OECD Guideline No. 105 (flask method).

The result is: Solubility in water = 24.5 mg/l at 20°C

 This result corresponds to the saturation mass concentrations of GR-88-0778 in ultrapure water at 20°C.

Description of key information

The solubility of GR-88-0778 in ultrapure water was determined according to the OECD Guideline No. 105 (flask method).

Key value for chemical safety assessment

Water solubility:
24.5 mg/L
at the temperature of:
20 °C

Additional information