Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 952-480-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Short-term aquatic toxicity data are available from a read-across for three trophic levels (fish, invertebrates and alga). The lowest acute is a 48-h EC50 of 3.8 mg/L in algae (Desmodesmus subspicatus). Since the lowest acute toxicity value is > 1 mg/L, the substance does not need to be classified as acute aquatic toxic according to EU CLP (EC no. 1272/2008 and its amendments: Table 4.1.0; a).
Long-term aquatic toxicity data are available only from a read-across to a study with algae Desmodesmus subspicatus in which an ErC10 value of 1.1 mg/L was derived. Furthermore, the substance is classified as not readily biodegradable. The log Kow is 4.9 (no experimentally determined BCF value is available). According to EU CLP Figure 4.1.0, the chronic classification has to be determined based on the chronic value for algae according to Table 4.1.0, (b) i, as well as the lowest acute value for the other tropic levels according to Table 4.1.0, (b) iii, and the most stringent outcome should be leading:
- The substance has a chronic toxicity value of > 1 mg/L. Based on this information, the substance does not need to be classified as Aquatic Chronic, according to Table 4.1.1, (b) i.
- The lowest acute toxicity value falls between > 1 but ≤ 10 mg/L but is not readily biodegradable and has a log Kow > 4 (4.9). Based on this information, the substance needs to be classified as Aquatic Chronic Cat. 2 according to Table 4.1.0, (b) iii.
Overall, it can be concluded that the substance needs to be classified as Aquatic Chronic Category 2, H411 (Toxic to aquatic life with long lasting effects) according to EU CLP (EC 1272/2008 and its amendments.
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