Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
EC Number:
700-093-4
Cas Number:
176969-34-9
Molecular formula:
C6H6F2N2O2
IUPAC Name:
3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
Details on test material:
Due to the fast hydrolysis of the subtance subject to this registration dossier, the water solubility was determinded using the corresponding free acid.

Results and discussion

Water solubilityopen allclose all
Water solubility:
3.13 g/L
Temp.:
20 °C
pH:
2.9
Remarks on result:
other: in distilled water
Water solubility:
455 g/L
Temp.:
20 °C
pH:
7
Remarks on result:
other: in buffered solution, pH 7

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)

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