Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

There is a single, key study for sensitization of the aromatic sulphonic acids. None of the tested animals showed positive responses in a, well documented, GLP guinea pig sensitization study (Hoechst, 1988) with toluene-4-sulphonic acid (CAS No. 104-15-4). The test substance can be considered a non-sensitizer in guinea pigs as none of the test animals showed a positive response to combined intradermal and topical induction followed by topical challenge


Migrated from Short description of key information:
Not sensitizing

Justification for classification or non-classification

There is no human or animal evidence on this endpoint therefore no classification is warranted under 67/548/EEC or Regulation 1272/2008.