Registration Dossier
Registration Dossier
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EC number: 212-855-9 | CAS number: 873-94-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Twenty female guinea pigs were treated with 3 identical inductions on days 0, 7, and 14 (occlusive epicutaneous) of undiluted 3,3,5 -trimethylcyclohexanone. Ten control animals were similary treated with vehicle. Two weeks after induction all animals were challegend with undiluted test material and the vehicle. Under the conditions of this study 3,3,5 -trimethylcyclohexanone showed no dermal sensitization in female guinea pigs.
Migrated from Short description of key information:
The skin sensitizing properties of 3,3,5-trimethylcyclohexanone were assessed in a Buehler test according to OECD 406 (Hüls, 1997). Under the conditions of this study 3,3,5 -trimethylcyclohexanone showed no dermal sensitization in female guinea pigs.
Justification for classification or non-classification
No sensitizing potential was reported in an OECD 406 study conducted under GLP.
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