Registration Dossier

Diss Factsheets

Manufacture, use & exposure

Uses at industrial sites

Documentsopen allclose all

Uses at industrial sites

Contributing activity / technique for the environment
Environmental release category (ERC):
ERC6a: Use of intermediate
Contributing activity / technique for workers
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Product category used:
PC 19: Intermediate
Sector of end use:
SU 9: Manufacture of fine chemicals
Substance supplied to that use in form of:
as such
Subsequent service life relevant for this use:
no

Uses at industrial sites

Registration/ Notification status for the use:
use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Reference
Name:
2-(Chloromethyl)-4-methylquinazoline
Type of composition:
boundary composition of the substance
State / form:
solid: particulate/powder
Reference substance:
2-(Chloromethyl)-4-methylquinazoline
Contributing activity / technique for the environment
Name of activity / technique:
Chemical Processing of Powder
Environmental release category (ERC):
ERC6a: Use of intermediate
Contributing activity / technique for workersopen allclose all
Name of activity / technique:
Chemical reaction to CD 616
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Name of activity / technique:
Filling, cleaning, filter maintenance and disposal of containers
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Name of activity / technique:
Laboratory Use
Process category (PROC):
PROC 15: Use as laboratory reagent
Sector of end use:
SU 0: Other: precursor to active pharmaceutical ingredient
Substance supplied to that use in form of:
as such
Subsequent service life relevant for this use:
no
Related assessment:
use assessed in an own CSR

Contributing scenario for the environment (related to workers activities)

Conditions of use for the environment

Amounts used, frequency and duration of use (or from service life)

Other conditions

Conditions and measures related to Biological Sewage Treatment Plant

Biological Sewage Treatment Plant (STP):
no
Other conditions of use

Conditions and measures related to external treatment of waste (including article waste)

Particular considerations on the waste treatment operations:
no

Other conditions affecting environmental exposure

Other conditions of use

Releases to waste and the environment

Release to the environment

ReleaseEnvirRepopen allclose all
Release from the site to::
surface water
Release estimation method:
estimated release factor
Remarks:
Release estimate
Release from the site to::
ambient air
Release estimation method:
estimated release factor
Remarks:
Release estimate
Release from the site to::
non-agricultural soil
Release estimation method:
estimated release factor
Remarks:
No soil exposure

Release to external waste

Exposure of the environment

PECopen allclose all
Exposed compartment:
freshwater
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sediment (freshwater)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
marine water
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sediment (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sewage treatment plant
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
air
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
agricultural soil
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (freshwater)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
top predators' prey (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (terrestrial)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
ContribScenWorkersRepopen allclose all

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with medium dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechMeansContainmentRepopen allclose all

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal

Other conditions affecting workers exposure

Place of use:
indoor

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with medium dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechMeansContainmentRepopen allclose all

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal

Other conditions affecting workers exposure

Place of use:
indoor

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with medium dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechMeansContainmentRepopen allclose all

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal

Other conditions affecting workers exposure

Place of use:
indoor
Other conditions of use

Uses at industrial sites

Registration/ Notification status for the use:
use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
Name of activity / technique:
Chemical Processing of Powder
Environmental release category (ERC):
ERC6a: Use of intermediate
Contributing activity / technique for workersopen allclose all
Name of activity / technique:
Chemical reaction to CD 616
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Name of activity / technique:
Filling, cleaning, filter maintenance and disposal of containers
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Name of activity / technique:
Laboratory Use
Process category (PROC):
PROC 15: Use as laboratory reagent
Sector of end use:
SU 0: Other: precursor to active pharmaceutical ingredient
Substance supplied to that use in form of:
as such
Subsequent service life relevant for this use:
no
Related assessment:
use assessed in an own CSR

Contributing scenario for the environment (related to workers activities)

Conditions of use for the environment

Amounts used, frequency and duration of use (or from service life)

Other conditions

Conditions and measures related to Biological Sewage Treatment Plant

Biological Sewage Treatment Plant (STP):
site specific biological STP
Application of site specific biological STP sludge on agricultural soil:
no
Other conditions of use

Conditions and measures related to external treatment of waste (including article waste)

Particular considerations on the waste treatment operations:
no

Other conditions affecting environmental exposure

Releases to waste and the environment

Release to the environment

ReleaseEnvirRepopen allclose all
Release from the site to::
wastewater
Release estimation method:
estimated release factor
Remarks:
Release estimate
Release from the site to::
ambient air
Release estimation method:
estimated release factor
Remarks:
Release estimate
Release from the site to::
non-agricultural soil
Release estimation method:
estimated release factor
Remarks:
No soil exposure

Release to external waste

Exposure of the environment

PECopen allclose all
Exposed compartment:
freshwater
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sediment (freshwater)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
marine water
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sediment (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sewage treatment plant
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
air
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
agricultural soil
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (freshwater)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
top predators' prey (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (terrestrial)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
ContribScenWorkersRepopen allclose all

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with medium dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechMeansContainmentRepopen allclose all

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal

Other conditions affecting workers exposure

Place of use:
indoor
Other conditions of use

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with medium dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechMeansContainmentRepopen allclose all

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal

Other conditions affecting workers exposure

Place of use:
indoor
Other conditions of use

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with medium dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechMeansContainmentRepopen allclose all

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal

Other conditions affecting workers exposure

Place of use:
indoor
Other conditions of use

Uses at industrial sites

Reference
Name:
2-Chloromethyl-4-methylquinazoline (CD605BS)
Type of composition:
legal entity composition of the substance
State / form:
solid: particulate/powder
Reference substance:
2-Chloromethyl-4-methylquinazoline (CD605BS)
Contributing activity / technique for the environment
Environmental release category (ERC):
ERC6a: Use of intermediate
Contributing activity / technique for workersopen allclose all
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Process category (PROC):
PROC 15: Use as laboratory reagent
Sector of end use:
SU 9: Manufacture of fine chemicals
Subsequent service life relevant for this use:
no