Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 476-280-7 | CAS number: 109113-72-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
General advice: Remove from exposure, lie down. Take off immediately all contaminated clothing. Victim to lie down in the recovery position, cover and keep him warm. First Aid responders should pay attention to self-protection and use the recommended protective clothing
If inhaled: Move to fresh air. Call a physician immediately.
In case of skin contact: Wash off immediately with plenty of water. Cover wound with sterile dressing. Call a physician immediately.
In case of eye contact: Rinse immediately with plenty of water for at least 15 minutes. Keep eye wide open while rinsing. Call a physician immediately.
If swallowed: Rinse mouth. Drink plenty of water. Call a physician immediately.
Most important symptoms and effects, both acute and delayed
Risks: No information available.
Indication of any immediate medical attention and special treatment needed
Treatment: Symptomatic treatment (decontamination, vital functions).
Fire-fighting measures
Suitable extinguishing media: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Water, Carbon dioxide (CO2), Dry chemical, Foam
Specific hazards during fire-fighting: In case of fire and/or explosion do not breathe fumes. Can be released in case of fire: Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Special protective equipment for firefighters: Self-contained breathing apparatus (EN 133) complete suit protecting against chemicals
Further information: Avoid generating dust; fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Collect contaminated fire extinguishing water separately. This must not be discharged into drains. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations.
Accidental release measures
Personal precautions: Wear personal protective equipment. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Knock down dust with water spray jet.
Environmental precautions: Do not flush into surface water or sanitary sewer system.
Methods for cleaning up: Wear personal protective equipment. Dust deposits should not be allowed to accumulate on surfac-es, as these may form an explosive mixture if they are re-leased into the atmosphere in sufficient concentration. Non-sparking tools should be used. Avoid dispersal of dust in the air (i.e., clearing dust surfaces with compressed air).
Clean-up methods - large spillage: Dampen, pick up mechanically and dispose of.
Clean-up methods - small spillage: Use approved industrial vacuum cleaner for removal.
Keep in suitable, closed containers for disposal.
Handling and storage
Advice on safe handling: Provide sufficient air exchange and/or exhaust in work rooms. Routine housekeeping should be instituted to ensure that dusts do not accumulate on surfaces. Minimize dust generation and accumulation. Dry powders can build static electricity charges when subjected to the friction of transfer and mixing operations. Provide adequate precautions, such as electrical grounding and bonding, or inert atmospheres. Breathing must be protected when large quantities are decanted without local exhaust ventilation. Keep container closed when not in use.
Advice on protection against fire and explosion: Keep away from heat and sources of ignition. Take precautionary measures against static discharges. Avoid dust formation.
Hygiene measures: General industrial hygiene practice. Wash hands and face before breaks and immediately after handling the product. Keep working clothes separately.
Conditions for safe storage, including any incompatibilities
Requirements for storage areas and containers: Keep tightly closed in a dry and cool place. Keep in a well-ventilated place. Protect from heat and direct sunlight. Joint-less smooth floor
Advice on common storage: Keep away from food, drink and animal feedingstuffs. Advice on Segregation
Storage class (TRGS 510): 11, Combustible Solids
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (2-Chloromethyl-4-methyl-quinazoline)
- Labels:
- 9
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (2-Chloromethyl-4-methyl-quinazoline)
- Labels:
- 9
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- Environmentally hazardous substance, solid, n.o.s. (2-Chloromethyl-4-methyl-quinazoline)
- Labels:
- Miscellaneous Dangerous Goods
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
1. Technical protection measures: It is recommended that all dust control equipment such as local exhaust ventilation and material transport systems involved in handling of this product contain explosion relief vents or an explo-sion suppression system or an oxygen deficient environment. Ensure that dust-handling systems (such as exhaust ducts, dust collectors, vessels, and pro-cessing equipment) are designed in a manner to prevent the escape of dust into the work area (i.e., there is no leakage from the equipment). Use only appropriately classified electrical equipment and powered industrial trucks.
2. Organisational protection measures: Handle in accordance with good industrial hygiene and safety practice. Do not breathe dust. Avoid contact with skin, eyes and clothing. Only use protective equipment in accordance with nation-al/international regulations. Follow the national regulations about wearing personal protective equipment and the warran-ty given by the manufacturer for the safe function.
3. Hand protection:
Material: Nitrile rubber
Break through time: 480 min
Glove thickness: 0,43 mm
Directive: Protective gloves against chemicals and micro-organisms
Protective index: Class 6
4. Feet protection: -
5. Body protection: chemical-protection suit, Laboratory: laboratory coat
6. Eye protection: Safety glasses with side-shields
7. Respiratory protection: Respirator with a dust filter particle filter P3 (EN 143)
Stability and reactivity
Reactivity: No dangerous reaction known under conditions of normal use.
Chemical stability: No decomposition if stored and applied as directed.
Possibility of hazardous reactions: Dust can form an explosive mixture with air.
Conditions to avoid: No data available
Materials to avoid: No data available
Hazardous decomposition products: No data available
Disposal considerations
Waste treatment methods
Product: Dispose of in accordance with local regulations.
Contaminated packaging: Packs that cannot be cleaned should be disposed of in the same manner as the contents. Uncontaminated packaging can be recycled.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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