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Ecotoxicological information

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The submission substance was assessed for possible aquatic toxicity in reliable tests (all reliability category 1) on freshwater algae (Scenedesmus subspicatus), freshwater invertebrates (Daphnia magna, acute), freshwater fish (zebra fish, acute) and sewage treatment plant microorganisms (activated sludge respiration inhibition test, 3 hours). In all these tests, nominal limit concentrations far above the actual water solubility of the submission substance were used (77 or 1000 mg/L). However, no signs of toxicity were observed in any of these tests. Thus, judging from these results terrestrial toxicity of the submission substance is unlikely. To ascertain this and in line with REACH guidance R.7c, chapter R.7.11.5, a possible chronic toxicity of the submission substance on earthworm reproduction was assessed. In the reliable (reliability category 1) test performed compliant to GLP no statistically significant effects on mortality, biomass or reproduction of Eisenia fetida were observed up to the highest tested concentration. Thus, the NOEC (56 d; mortality, biomass, reproduction) was determined to be larger or equal to 1000 mg/kg soil dw. In conclusion, taking together nontoxic properties of the submission substance towards aquatic (micro)organisms as well as soil macroorganisms (chronic test), toxicity of the submission substance towards terrestrial organisms can safely be precluded.