Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 234-666-0 | CAS number: 12021-95-3
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
Because the substance H2ZrF6 is a highly corrosive liquid (Skin Corr. 1A, H314: Causes severe skin burns and eye damage), no experimental studies investigating skin sensitisation are available. Further, read-across is applied from the solid salt dipotassium hexafluorozirconate (K2ZrF6), which was shown not to be sensitising in a guideline conform study according to OECD Guideline 406 (guinea pig maximisation study, Reference: Allen, D.J. (1997)). No classification for skin sensitisation is required for H2ZrF6.
Justification for selection of skin sensitisation endpoint:
Read-across to H2ZrF6 (no testing possible because of corrosivity) from non-corrosive salt dipotassium hexafluorozirconate based on structural similarities.
Justification for classification or non-classification
Because the substance H2ZrF6 is a highly corrosive liquid (Skin Corr. 1A, H314: Causes severe skin burns and eye damage), no experimental studies investigating skin sensitisation are available. Further, read-across is applied from the solid salt dipotassium hexafluorozirconate (K2ZrF6), which was shown not to be sensitising in a guideline conform study according to OECD Guideline 406 (guinea pig maximisation study, Reference: Allen, D.J. (1997)). No classification for skin sensitisation is required for H2ZrF6.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
