Registration Dossier
Registration Dossier
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EC number: 200-296-3 | CAS number: 56-89-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The test item L-Cystine had no acute toxic effects on Daphnia magna up to its solubility limit in test water under the test conditions.
The EC50 is > 100 mg/L.
Key value for chemical safety assessment
Additional information
The 48-hour NOEC and 48-hour EC0 of L-Cystine to Daphnia magna were determined to be at least the loading rate of 100 mg/L. The 48-hour NOEC and 48-hour EC0 might even be higher, but concentrations above the loading rate of 100 mg/L were not tested, in accordance with the test guidelines. The 48-hour EC50 and the 48-hour EC100 were clearly higher than the loading rate of 100 mg/L. These values could not be quantified due to the absence of toxicity of L-Cystine at the loading rate of 100 mg/L.
In conclusion, the test item L-Cystine had no acute toxic effects on Daphnia magna up to its solubility limit in test water under the test conditions. The 48-hour NOEC and 48-hour EC0 of L-Cystine to Daphnia magna were determined to be at least the loading rate of 100 mg/L in a limit test according to OECD Guideline 202.
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