Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

genetic toxicity in vivo
Rationale for reliability incl. deficiencies:
other: see 'Remark'
L-Cystine does not need to be classified for genetic toxicity in vitro. The read-across is justified due to the rapid conversion of L-Cysteine to L-Cystine and due to the fact that in many proteins two molecules of L-Cysteine form a disulfide bridge resulting in L-Cysteine. The mechanisms are described in detail in other sections of this CSR.
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion