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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The acute toxicity of Piperonyl butoxide to aquatic invertebrates (Daphnia magna)  was determined in a semi-static test conducted according to OECD 202 (2004) guideline. A series of 8 concentrations with 20 organisms per test concentration was tested for 48 h. Potassium dichromate was tested as a reference substance. Immobilisation was observed. The EC50 (48 h) was 1.007 mg/L and the NOEC (48 h) was 0.515 mg/L. This study was assessed as"reliable without restriction"

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1.007 mg/L

Additional information

The study of Borrmann, K. (2009) was conducted according to OECD 202 (2004) guideline and was found to be valid with EC50of 1.007 mg of Piperonyl butoxide/L (nominal) for Dapnia magna after 48 hours. The study is considered as "reliable without restriction".

The results are summarised in the following table:

 Species Endpoint (exposure duration) Exposure concentration  Reference
 Daphnia magna  EC50(48 h)  1.007 mg/L Borrmann, K. (2009)
 Daphnia magna  NOEC (48 h)  0.515 mg/L
Borrmann, K. (2009)