Registration Dossier
Registration Dossier
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EC number: 200-076-7 | CAS number: 51-03-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of Piperonyl butoxide to aquatic invertebrates (Daphnia magna) was determined in a semi-static test conducted according to OECD 202 (2004) guideline. A series of 8 concentrations with 20 organisms per test concentration was tested for 48 h. Potassium dichromate was tested as a reference substance. Immobilisation was observed. The EC50 (48 h) was 1.007 mg/L and the NOEC (48 h) was 0.515 mg/L. This study was assessed as"reliable without restriction"
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1.007 mg/L
Additional information
The study of Borrmann, K. (2009) was conducted according to OECD 202 (2004) guideline and was found to be valid with EC50of 1.007 mg of Piperonyl butoxide/L (nominal) for Dapnia magna after 48 hours. The study is considered as "reliable without restriction".
The results are summarised in the following table:
| Species | Endpoint (exposure duration) | Exposure concentration | Reference |
| Daphnia magna | EC50(48 h) | 1.007 mg/L | Borrmann, K. (2009) |
| Daphnia magna | NOEC (48 h) | 0.515 mg/L |
Borrmann, K. (2009) |
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