Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
trans-1,4-bis(iodomethyl)cyclohexane
Cas Number:
83447-96-5
Molecular formula:
C8H14I2
IUPAC Name:
trans-1,4-bis(iodomethyl)cyclohexane

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
sewage, domestic (adaptation not specified)
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
6.7 mg/L
Based on:
test mat.
Reference substance
Reference substance:
other: sodium acetate anhydrous

Results and discussion

% Degradationopen allclose all
Parameter:
% degradation (O2 consumption)
Value:
0
Sampling time:
2 d
Parameter:
% degradation (O2 consumption)
Value:
0
Sampling time:
5 d
Parameter:
% degradation (O2 consumption)
Value:
1
Sampling time:
12 d
Parameter:
% degradation (O2 consumption)
Value:
0
Sampling time:
28 d
Details on results:
For the test item, no reduction of the O2 concentration was observed. Throughout the experiment not any O2 uptake were measured.
The degradation of the toxicity control showed about the same run as the procedure control indicating that the concentration of the test item had no inhibitory effect.

BOD5 / COD results

Results with reference substance:
The percentage degradation of the reference compound has reached the pass level of 60 per cent on day 5.
The residual concentration of oxygen did not fall below 0.5 mg/I.

Applicant's summary and conclusion

Conclusions:
In the present study not any oxygen uptake by the test item was measured. The pass level for ready biodegradation (60 per cent degradation) was notreached. For this reason in the test for ready biodegradability the test item seems to be not readily biodegradable.