Registration Dossier
Registration Dossier
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EC number: 807-374-1 | CAS number: 2540-36-5
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicological Profile for carbon disulfide
- Author:
- U.S. Department of Health and Human Services
- Year:
- 1 996
- Bibliographic source:
- U.S. Department of Health and Human Services . Public Health Service . Agency for Toxic Substances and Disease Registry
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 471 (Bacterial Reverse Mutation Assay)
Test material
- Reference substance name:
- carbon disulfide
- IUPAC Name:
- carbon disulfide
- Reference substance name:
- Carbon disulphide
- EC Number:
- 200-843-6
- EC Name:
- Carbon disulphide
- Cas Number:
- 75-15-0
- IUPAC Name:
- dithioxomethane
Constituent 1
Constituent 2
Results and discussion
Test resultsopen allclose all
- Species / strain:
- S. typhimurium, other: no data
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Species / strain:
- E. coli, other:
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Species / strain:
- S. typhimurium TA 98
- Metabolic activation:
- not specified
- Genotoxicity:
- negative
- Species / strain:
- other: Human WI-38 cells
- Genotoxicity:
- negative
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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