Registration Dossier
Registration Dossier
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EC number: 807-374-1 | CAS number: 2540-36-5
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Toxicological Profile for Carbon Disulfide ,
- Author:
- U.S. Department of Health and Human Services
- Year:
- 1 996
- Bibliographic source:
- U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Carbon disulfide
- IUPAC Name:
- Carbon disulfide
- Reference substance name:
- Carbon disulphide
- EC Number:
- 200-843-6
- EC Name:
- Carbon disulphide
- Cas Number:
- 75-15-0
- IUPAC Name:
- dithioxomethane
Constituent 1
Constituent 2
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- inhalation
Doses / concentrations
- Remarks:
- Doses / Concentrations:
750 ppm
Basis:
no data
Results and discussion
Results: maternal animals
Effect levels (maternal animals)
- Dose descriptor:
- other:
- Basis for effect level:
- other: effect type not specified
Results (fetuses)
Fetal abnormalities
- Abnormalities:
- not specified
Overall developmental toxicity
- Developmental effects observed:
- not specified
Any other information on results incl. tables
Carbon disulfide and its metabolite pass the placenta at all stages of gestation and localize in brain blood liver and eye. Carbon disulfide or its metabolites may effects directly on the embryo.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
