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EC number: 941-718-2
CAS number: -
data is being read across from the source study that tested
Hydrocarbons, C8-C11, n-alkanes, isoalkanes, <2% aromatics based on
analogue read across.
Acute eye irritation/corrosion study
with Hydrocarbons, C8-C11, n-alkanes, isoalkanes, <2% aromatics in the
The study was carried out based on the
guidelines described in:
OECD No.405 (2012) "Acute Eye
Irritation / Corrosion"
EC, No 440/2008, B5: "Acute Toxicity:
EPA, OPPTS 870.2400 (1998): "Acute Eye
JMAFF Guidelines (2000), including the
most recent revisions.
Single samples of 0.1 mL of
Hydrocarbons, C8-C11, n-alkanes, isoalkanes, <2% aromatics were
instilled into one eye of each of three rabbits. Observations were made
1, 24, 48 and 72 hours after instillation.
Instillation of the test substance
resulted in irritation of the conjunctivae, which consisted of redness
in all animals and discharge in one animal. The irritation had
completely resolved within 24 hours in all animals.
Based on these results, Hydrocarbons,
C8-C11, n-alkanes, isoalkanes, <2% aromatics does not have to be
classified and has no obligatory labelling requirement for eye
irritation according to the:
Harmonized System of Classification and Labelling of Chemicals (GHS) of
the United Nations (2011)(including all amendments),
(EC) No 1272/2008 on classification, labelling and packaging of
substances and mixtures (including all amendments).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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