Registration Dossier
Registration Dossier
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EC number: 617-441-5 | CAS number: 83121-18-0
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Teflubenzuron was assessed for degradation over a period of 28 days using the Modified Sturm Test (OECD 301B). Teflubenzuron was added directly to the test vessels at 25 mg/L and 50 mg/L. Under the conditions of the modified Sturm test, teflubenzuron is not classified as a “readily biodegradable” substance.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
Two studies on the ready biodegradability of teflubenzuron are available.
For details please refer to Draft Assessment Report for teflubenzuron prepared according to the Commission Regulation (EU) No 1107/2009, Volume 3 – B.8 (AS) (October 2007).
Acer Environmental (1994a): The Biodegradation of Teflubenzuron in the Modied Sturm Test. DocID according to Draft Assessment Report prepared in compliance with Regulation (EC) No 1107/2009: TZ-690-001; crossreference to Draft Assessment Report according to Regulation (EU) No 1107/2009: CA 7.2.1.3.1/01
The biodegradability of teflubenzuron was determined in a GLP compliant study according to OECD 301B over a 8 day period in the Modified Sturm Test at nominal concentrations of 25 mg/L and 50 mg/L at 20°C. Measurements of evolved CO2 were made on Days 3, 7, 14, 21 and 28. Sodium benzoate was used as a reference material. At 25 mg/L and 50 mg/L no significant degradation was observed compared to sodium benzoate. Under the conditions of the modified Sturm test, teflubenzuron is not classified as a “readily biodegradable” substance.
The second study is summarized in the following for sake of completeness but has however not been documented in a separate IUCLID Endpoint Study Record.
Acer Environmental (1994b): Study of the Biodegradability of Teflubenzuron using the Anaerobic Gas Production Test. DocID: TZ-690-002; crossreference to Annex I Dossier according to Regulation (EU) No 1107/2009: CA 7.2.1.3.1/02
The biodegradability of teflubenzuron was determined in a GLP comliant study according to ISO/TC147/SC5/WG4 N172, EXETOC N0. 28, over a 56 day period in an anaerobic biogas production test at a concentration of 11.36 mg/flask (5 mg carbon per flask) at 35°C. Measurements of headspace pressure and dissolved inorganic carbon were made weekly. Sodium benzoate was used as a reference material. The pattern was not clearly shown as high gas production occurred in all the vessels including the controls. The values at 56 days for degradation due to headspace gas were 39.8%, and for total degradation were 33.2%. Limited degradation of teflubenzuron occurred in an anaerobic biogas production test at 35 °C.
Conclusion
Teflubenzuron was assessed in two screening tests, one according to OECD 301B, the other according to ISO/TC147/SC5/WG4 N172, EXETOC No. 28. No significant degradation was observed in the modified Sturm Test, and only limited degradation was observed in the anaerobic biogas test. Therefore teflubenzuron is considered not to be readily biodegradable.
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