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Description of key information

Hydrolysis of the test item is rapidly completed. Neither the determination of hydrolysis rates according to OECD TG 111 (2004) nor the detection of hydrolysis products was possible. 
In the filtrate of the solubility test no test item could be detected. The precipitating solid is not identical with the test item. Only traces of isocyanates could be found (Currenta, 2010a).
Toluene diisocyanate undergoes heterogeneous interaction with water whereas the kinetics and the product distribution strongly depends on the degree of agitation, the surface area of the substance and the stoichiometric conditions. It was shown that toluene diamine and insoluble polyurea were amongst others formed as reaction products, but only with good agitation and low loadings, TDA will be the main reaction product. Otherwise, insoluble polyurea compounds are formed. (Yakabe, 1999)

Key value for chemical safety assessment

Additional information

No test conditions could be found enabling the performance of a hydrolysis study for the substance according to OECD TG 111 (2004).

- As the test item is characterized by the presence of isocyanate groups, hydrolysis reactions have to be assumed. Although it was not possible to separate between the insolubility effect and a hydrolysis it has to be assumed that hydrolysis occurs immediately within a few hours after contact with water.

- The test item is not sufficiently soluble in water and precipitates immediately when mixed with water.

-The test item is a No-Longer-Polymer (NLP). As it consists of different fractions, several peaks were observed in the chromatograms of the test item in organic solutions. The response is therefore spread over few peaks which decreases the sensitivity of the analytical method hampering the detection of peaks in the required concentration range. Additionally, a distinct hydrolysis behaviour of the different fractions has to be assumed.