Registration Dossier
Registration Dossier
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EC number: 402-400-4 | CAS number: 54660-00-3
Endpoint summary
Administrative data
Description of key information
Additional information
Acute tests on all three trophic levels were performed to examine the aquatic toxicity of the test substance. The L(E)C 50 values for fish, daphnia, algae and activated sludge were not quantifiable due to the lack of toxic effects in the respective studies. Additionally, long-term tests on the aquatic toxicity to fish and daphnids with an analogous substance are available. No effects occurred within the range of water solubility.
Thus, the compound is considered with high probability acutely not harmful to aquatic organisms in the range of water solubility.
Acute toxicity to fish:
The LC0 value of an OECD guideline study on zebra fish was determined to be greater than 100 mg/L (CIBA-GEIGY 1985, nominal value was verified by analytical measurement).
Long-term toxicity to fish:
The long-term toxicity of an analogous substance (EC 401 -540 -3) to Rainbow trout has been tested according to OECD 204 (CIBA-GEIGY 1990a). The overall NOEC exceeded the range of water solubility.
Acute toxicity to aquatic invertebrates:
In a short-term toxicity study of the test substance on daphnids (24h) no toxic effects occurred at the highest test concentration of nominally 100 mg/L (CIBA-GEIGY 1986b). Although there was evidence of a precipitation of the test substance after 24 hours, it can be assumed that there was no toxicity in the range of the low water solubility of the test substance. Therefore, the test substance is considered not to be harmful to daphnids.
Long-term toxicity to aquatic invertebrates:
The long-term toxicity of an analogous substance (EC 401 -540 -3) to Daphnia magna has been tested according to OECD 202, Part II (CIBA-GEIGY 1990b). The overall NOEC for reproduction exceeded the range of water solubility.
Toxicity to aquatic algae:
In an algae study (72 h) according to OECD 201 no inhibition of algae growth, expressed as biomass and growth rate was observed at the highest test concentration of 100 mg/L nominal (CIBA-GEIGY 1995a). The mean measured concentration (0.072 mg/L) of the test substance was found to at least match or even exceed the water solubility of the test item (< 0.07 mg/L).
Toxicity to microorganisms:
The EC50 value of the test substance on activated sludge according to OECD 209 was found to be greater than 100 mg/L (nominal concentration, CIBA-GEIGY 1995b).
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