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Toxicity to soil macroorganisms except arthropods

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Key value for chemical safety assessment

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Data on the toxicity to the earthworm Eisenia foetida of an analogous substance (EC 401-540-3) are available (CIBA-GEIGY 1990c) . With a LC0 greater than 1000 mg/kg dry weight of soil, this information demonstrates that the toxicity of the test substance and its analogy, respectively, to soil macroorganisms is very low.

The read-across substance (EC 401-540-3) has similar physicochemical, toxicological and ecotoxicological properties. It is also of low water solubility and degradation and hydrolysis are not likely. Due to the inert structure no break-down products will occur in the environmental compartments.

The read-across substance differs by an additional chlorine in para-position of both phenyl rings. Therefore, the molecular diameter is slightly larger and the solubility in organic solvents expected to be slightly better. The common functional group is the 2,5 -dihydro-pyrrolo(3,4 -c)pyrrole-1,4 dione core. It is the chromophore that is both poorly soluble in organic and in inorganic solvents. The additional chlorines of the read-across substance may render it slightly better soluble in organic solvents. Additionally, it can be assumed based on the additional chlorines that the water solubility is predicted to be even lower and the logPow higher.