Nerol

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

September 2011

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Remarks:

This study was considered as reliable with restrictions because it was not conducted under GLP and there are some lack of details in the study report.

Reason / purpose for cross-reference:

reference to other study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

not specified

GLP compliance:

no

Type of method:

method to determine freezing temperature

Key result

Melting / freezing pt.:

< -20 °C

Atm. press.:

ca. 1 atm

Decomposition:

no

Sublimation:

no

After twelve hours of storage in a freezer at - 20°C the test item was still liquid.

According to Annex VII of REACH, the study does not need to be conducted below a lower limit of - 20°C. Therefore no main study was performed and the determination was terminated.

Conclusions:

No freezing point or range could be detected.
The freezing point of nerol was stated as < - 20°C.

Executive summary:

The determination of the melting point was performed in accordance with Regulation (EC) No 440/2008, method A.1 “Melting/Freezing Temperature” (May 2008) and OECD Guideline No 102 “Melting Point/Melting Range” (July 1995).

In a preliminary study, the test item was still not frozen after twelve hours of storage in a freezer at - 20°C; according to Annex VII of REACH, no main study was performed. The freezing point or range of nerol was stated as < - 20°C.

No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.

Description of key information

In a preliminary study, the test item was still not frozen after twelve hours of storage in a freezer at - 20°C.

Therefore, according to Annex VII of REACH, no main study was performed.
The freezing point or range of nerol is < - 20°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-20 °C

Additional information

Key study conducted according to OECD 102 and EU A.1 guidelines. The result is scientifically acceptable but not obtained under GLP.

Therefore a reliability of 2 (reliable with restrictions) was assigned.