2-aminobenzenesulphonic acid

Toxicity to aquatic algae and cyanobacteria

Description of key information

The no observed effect concentration (NOEC) value of 2-aminobenzenesulphonic acid in aquatic algae (Pseudokirchnerella subcapitata) in a 72 hrs study was estimated to be 0.3396714 mg/L.

Key value for chemical safety assessment

EC10 or NOEC for freshwater algae:

0.34 mg/L

Additional information

No. of studies were reviewed for toxicity to aquatic algae from reliable sources having Klimisch rating 2 and 4. 

The summary of the results are presented below   

Sr.No	Endpoint	Effect values	Basis for effects	Duration	Species	Sources
1.	NOEC	0.3396714mg/L	Growth	72 hrs.	Pseudokirchnerella subcapitata	Predicted data from QSAR for target CAS : 88-21-1
2.	EC50	198.373mg/l	-	96 hrs.	Green Algae	Predicted data from ECOSAR for target CAS : 88-21-1
3.	EC50	170 mg/l	Population	48 hrs.	Desmodesmus subspicatus (reported as Scenedesmus subspicatus)	Experimental data for read across CAS: 615-36-1

 

Based on the studies summarized in the above table for the target substance 2-aminobenzenesulphonic acid and the read across substance, the endpoint value was found to vary between EC50 = 170 mg/l to 198.373mg/l and NOEC =0.3396714mg/L in a 96,72 and 48 hrs.; on the basis of Population and growth effect. Based on the above weight of evidence values, it is concluded that the test substance dose not qualifies for the aquatic toxicity.