Registration Dossier

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Administrative data

Description of key information

Acute mammalian toxicity in rats, exposed by the oral gavage, inhalation and dermal routes

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
5 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
1.9 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
5 000 mg/kg bw

Additional information

During exposure of the substance by the oral, dermal and inhalation routes only a minor incidence of mortality was observed and never at a rate considered to be significant when dosing levels at or below the volumes specified above. Where significant mortality has been observed, this was observed at dose levels significantly higher than those specified above. The limit values expressed above are, therefore, considered appropriate.

Justification for classification or non-classification

As not significant mortality has been observed at the limit values expressed above, the substance is considered to be not classified as acutely toxic.