Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

The half-life for the photodegradation of ditolyl ether by reaction with hydroxyl radicals in air is estimated to be 0.62 days or 14.8 hours as estimated with AOPWIN (v1.91).


The substance does not contain any hydrolysable functional groups. No abiotic degradation of ditolyl ether was observed. Consequently ditolylether is assumed to be stable at 50 °C and pH 4, 7 and 9.


Ditolyl ether is not readily biodegradable when using unadapted inoculum from a wastewater treatment plant treating predominantly domestic sewage as shown in a Manometric Respirometry Test (OECD 301 D, 2 % after 28 days).

Ditolyl ether was not inherently biodegradable using activated sludge, mixture of domestic and industrial STP, in a modified MITI test (II) (OECD 302 C, 3 % after 28 days).


In an OECD 309 test performed with a mixture of the 6 isomers, five isomers were found to be degraded with DT50 values below 40°C at 12°C. The 2,2 -isomer however showed a longer half life of 63 days at 12°C.


The BCF of ditolyl ether was calculated from the read across substance diphenyl ether (CAS 101-84-8), using the data provided by the study of DOW Chemical Company, 1973, which were supported by valid QSAR estimation using EPIWIN. The read across BCF was determined to be 982. However, a final SEv decision has been issued by ECHA, requesting a BCF study depending on the outcome of the OECD 309 simulation study in water.    


An adsorption coefficient (log Koc) 4.0 was determined at pH 6. The result can be expected to be equal at 25 °C.


The Henry's Law Constant was calculated by HENRYWIN (v.3.20) to be 4.864 Pa m3/mol at 25°C.