Registration Dossier
Registration Dossier
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EC number: 629-720-9 | CAS number: 1219826-66-0
Endpoint summary
Administrative data
Description of key information
Additional information
The bioaccumulation potential for the branched triamine C16-18 is based on a measured log Kow of -0.3 for Oleyltetramine using the slow-stirring method (OECD 123). With this log Kow a BCF of 3.162 L/kg ww is calculated, assuming no metabolism. The calculated BCF indicates a low bioaccumulation potential. Branched triamine C16-18 is almost completely protonated under ambient conditions. In addition, the bioavailable fraction is quickly degraded and a chronic exposure to a significant concentration is therefore unlikely.The predicted low bioaccumulation potential is supported by the low acute to chronic ratio observed in the long-term daphnia test.
The daphnia reproduction test result shows that at 1 mg/L all parental daphnids were immobile within 11 days, with only one daphnia with one brood others did not reproduce, while at the next concentration of 320 µg/L not only is there no immobilisation, but there is no detrimental effect on reproduction when compared to the control. These observations results in the derivation of a NOEC of 320 µg/L resulting in a low acute-to-chronic ratio. A low acute-to-chronic ratio is indicative of a non-specific mode of action and is often associated with not systemic effects. This observation is consistent with the known effects of cationic surfactants on aquatic organisms, where toxicity is associated with physical binding to respiratory membranes. This explains the steep concentration curves seen and the lack of intermediate chronic effects on reproduction.Finally is the biodegradability a strong indication that these substances are also quickly metabolized.
In a chronic earthworm test no effects were observed up to a concentration of 1000 mg/kg (NOEC = 1000 mg/kg dw). This indicates a low bioaccumulation potential for the soil compartment despite the relatively high sorption.
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