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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed study according to guideline developed and agreed upon by the ETAD in january 2005 for colorants with very low solubility

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: method developed by ETAD
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
12H-phthaloperin-12-one
EC Number:
230-049-5
EC Name:
12H-phthaloperin-12-one
Cas Number:
6925-69-5
Molecular formula:
C18H10N2O
IUPAC Name:
12H-isoindolo[2,1-a]perimidin-12-one

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
n-octanol
Solubility:
317 mg/L
Temp.:
24 °C
Test substance stable:
yes
Details on results:
The determination was repeated three times and the average value was calculated from the individual results.
Individual results:
Absorption Solubility
(d = 1 cm n-octanol
dilution 1:50) mg/l
a1 0.191 311
a2 0.194 317
a3 0.199 324

Average: 317 mg/L

Applicant's summary and conclusion

Conclusions:
The solubility of the substance in n-octanol at 24°C is 317 mg/L
Executive summary:

The n-octanol solubility of the substance was determined 3 times according to the method developed by the ETAD at 24°C. The average of the results was 317 mg/L.