Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Test results are expressed in terms of Stimulation Indices, the ratios of the mean scintillation count per group obtained from the test groups relative to the corresponding mean scintillation count from controls. The threshold level for the Stimulation Index to be considered a positive indicator of the potential to cause skin sensitisation is 3.0.

Main study 1


Concentration of test article in applied formulation (% w/v)




Stimulation Index




Main study 2


Concentration of test article in applied formulation (% w/v)




Stimulation Index




Migrated from Short description of key information:
The skin sensitisation was investigated following OECD Guideline 429 and EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay).
The study was performed under GLP conditions.

Justification for classification or non-classification

The Local Lymph Node Assay demonstrated that Uvasorb HA 88 has the potential to cause skin sensitisation. The test article was classified as a Category 1 sensitiser according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).

Basing on the results above reported, REGULATION (EC) No 1272/2008 (EU Regulation on Classification, Labelling and Packaging of substances and mixtures) would indicate the following:


Skin sensitisation:

Classification : Skin sensitiser - Category 1

Signal word : Warning

Hazard statement (Oral) : H317: May cause an allergic skin reaction.