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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB


AHTN is Not T based on:

  • The lowest NOEC for aquatic organisms is 0.022 mg/l which does not meet the T-criterion of 0.01 mg/L. All toxicological tests performed on mammals only justify the classification Harmful when/if swallowed (R22 or H302), so AHTN does not meet any of the classifications mentioned for the T-criterion.


AHTN is Not B or vB based on:

  • Bioaccumulation factors determined in fish. The BCF in laboratory studies is circa 600; AHTN is readily metabilised and excreted; its transformation products are water soluble and have a low log Kow.
  • The low BCF is confirmed by BCFs derived from field studies.
  • Field studies did not show any indications for biomagnification of AHTN in the food chain.


AHTN is Not P or vP based on:

  • Although AHTN does not rapidly mineralize, the parent material steadily disappeared from river water with an overall half-life of circa 9 days. The loss due to biodegradation was 42% after 28 days. Biotransformation products are water soluble with log Kow < 4 (so they do not meet the 'B'-criterion. Other studies confirm the biodegradability of the substance.
  • With 42% primary biodegradation in a CAS test, AHTN is classified as 'inherently biodegradable'.
  • The environmental concentrations reflect the decreasing use volume of the substance, illustrating the AHTN is degraded in the STP/aquatic environment.
  • AHTN in sludge applied to soils disappeared fast.
  • Volatilisation may be a relevant pathway but in view of the rapid degradation under atmospheric conditions, AHTN has a short-lifetime in this compartment.

It is concluded that AHTN is not P.

Since AHTN is not T, not B or vB and not P, AHTN is not a PBT/vPvB substance.