Registration Dossier
Registration Dossier
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EC number: 216-133-4 | CAS number: 1506-02-1
Endpoint summary
Administrative data
Description of key information
Additional information
Tests are available for prolonged exposure of algae, invertebrates and fish. These studies were fully reported and conducted according to GLP requirements. The short-term values for fish and Daphnia were derived from the long term studies. It should be noted that the test animals were fed during the test. Additional data for short-term for marine species were taken from the EU Risk Assessment Report (2008) as these values were below the data for fish and Daphnia.
No specific toxicity tests on micro-organisms were conducted, but in the biodegradation test, no inhibition was observed up to 30 mg/l. The NOEC is set to 22 mg/l, which is far above the water solubility of AHTN.
Species |
Guideline |
Result (mg/l) |
Reference |
Remarks |
Algae |
|
|
|
|
Pseudokirchneriella subcapitata |
OECD 201 |
72h-ECr50 > 0.835 72h-NOECr = 0.40 |
Van Dijk 1997 |
Rel. 1 |
|
|
|
|
|
Invertebrates |
|
|
|
|
Nitocra spinipes (marine) |
|
96h-LC50 = 0.61 |
Breitholz et al 2003, in EU RAR 2008 |
Rel. 2 for the short-term part |
Acartia tonsa (marine) |
draft ISO/DIS 14669 |
48h-LC50 = 0.71 |
Wollenberger et al 2003, in EU RAR 2008 |
Rel. 2 for the short-term part |
Acartia tonsa (marine) |
OECD draft |
6d-EC10, larval dev. ratio = 0.028, NOEC = 0.022 |
Bjornestad 2007 |
Rel. 1 |
Daphnia magna |
OECD 202 |
3d-EC50 imm. > 0.80 |
Wütrich 1996a |
Rel. 2 |
|
OECD 202 |
21d-NOECrepr = 0.196 |
Wütrich 1996a |
Rel. 1 |
|
|
|
|
|
Fish |
|
|
|
|
Lepomis macrochirus |
OECD 204 |
4d-LC50 = 1.49 |
Wütrich 1996b |
Rel. 2 |
|
OECD 204 |
21d-NOECgrowth = 0.089 |
Wütrich 1996b |
Rel. 1 |
Pimephales promelas |
OECD 210 |
36d-NOEC = 0.035 |
Croudace et al 1997 |
Rel. 1 |
Brachydanio rerio |
OECD 210 |
34d-NOEC = 0.035 |
Hooftman et al 1999 |
Rel. 1 |
| Plants | ||||
| Dicotyledonous species: Beta vulgaris (sugar beet), Brassica napus (rape), Lycopersicon esculentum (tomato), Pisum sativum (pea) Monocotyledonous species: Allium cepa (onion), Lolium perenne (perennial ryegrass) |
OECD 208 | 21d NOEC <0.198 mg of act. ingr./kg soil dw (most sensitive species: Beta vulgaris) | Rippergen 2018 | Rel. 1 |
| Soil (nitrogen transformation) | OECD 2016 | 28d NOEC≥31.6 mg act. ingr. /kg soil dw | Hauser 2017 | Rel.1 |
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