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Toxicity to microorganisms

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Description of key information

The estimated 40-hr EL50 value for Tetrahymena pyriformis, one of the most sensitive aquatic microorganism species, is >1000 mg/L and the estimated NOEL is 2.492 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L
EC10 or NOEC for microorganisms:
2.492 mg/L

Additional information

The aquatic toxicity was estimated using the PETROTOX computer model, which combines a partitioning model (used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading) with the Target Lipid Model (used to calculate acute and chronic toxicity of non-polar narcotic chemicals). PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a petroleum substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism. The estimated 40-hr EL50 value forTetrahymena pyriformis, one of the most sensitive microorganism species, is >1000 mg/L and the estimated NOEL is 2.492 mg/L.