Registration Dossier
Registration Dossier
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EC number: 219-292-8 | CAS number: 2403-89-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- other: read across from 2,2,6,6 -tetramethylpiperidin-4 -ol (the analogue substance with no methyl group on N)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- See the summary of this endpoint
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- OECD SIDS 2,2’,6,6’-TETRAMETHYLPIPERIDIN-4-OL
- Author:
- OECD
- Year:
- 2 002
- Bibliographic source:
- OECD SIDS 2,2,6,6-Tetramethylpiperidin-4-ol (CAS 2403-88-5)
- Report date:
- 2002
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,2,6,6-tetramethylpiperidin-4-ol
- EC Number:
- 219-291-2
- EC Name:
- 2,2,6,6-tetramethylpiperidin-4-ol
- Cas Number:
- 2403-88-5
- Molecular formula:
- C9H19NO
- IUPAC Name:
- 2,2,6,6-tetramethylpiperidin-4-ol
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Score:
- 5.5
- Max. score:
- 8
- Reversibility:
- not reversible
- Remarks on result:
- other: highly irritating
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (corrosive) based on GHS criteria
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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